NEW Osteoporosis And Postmenopausal Pharmaceuticals Planned For Release
by CF Thompson
Amgen NASDAQ: AMGN pharmaceutical powerhouse just announced positive performance results for denosumab Pivotal Postmenopausal Osteoporosis Trial.
Study reached primary endpoint of Diminishing new vertebral fractures and secondary endpoints of reducing time to first non-vertebral and hip fractures; adverse events similar to placebo. The past president of the National Osteoporosis Foundation was excited." I am particularly excited about these findings because they indicate that denosumab may offer an important new option for patients."
Denosumab is the first fully human monoclonal antibody in late stage clinical development that specifically targets RANK Ligand, an important regulator of osteoclasts (these are the cells that break the bone down). Denosumab is being considered for its potential to inhibit all stages of osteoclast activity by a targeted mechanism. Denosumab is being researched in a range of bone loss conditions including postmenopausal osteoporosis, rheumatoid arthritis, and cancer treatment-induced bone loss in breast cancer and prostate cancer patients| in prostate cancer and breast cancer patients as well as for its ability to defer bone metastases and inhibit and treat bone destruction for many stages of cancer.
Often referred to as the "silent epidemic", osteoporosis is a world wide problem illness, which is growing in dominance as the world population both increases and ages. The World Health Organization (WHO) has recently identified osteoporosis as a significant health issue along with other major non-communicable diseases. We are dependent on the pharmaceutical industry to help combat this horrendous disease.
According to Amgen the financial burden of osteoporosis is compared to as the "silent epidemi' to that of other major chronic diseases; for example, in the U.S. the costs associated with osteoporosis-related fractures are equivalent to those of cardiovascular disease and asthma (i)(ii)(iii). It has been reported that osteoporosis results in more hospital bed-days than stroke, myocardial infarction or breast cancer (iv).
Pharmacist-clinical have been developing prescriptions drugs to help patient that have serious side effects. These products are created simultaneously the medications that aid in the treatment of the primary illness. The fact that research is available to help anticipate the potential side effects and interactions drugs have with each other is awesome.
There are several drugs that both, prevent and treat osteoporosis. Some medicines slow the rate of bone loss or increase bone thickness. Even small amounts of new bone growth can reduce the danger of broken bones. It is important that you take calcium and vitamin D, exercise and eat well when you take osteoporosis prescriptions.
prescription drug
Published July 25th, 2008
Filed in Health, Women
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